Reactome | FAAH hydrolyses AEA to AA and ETA

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FAAH hydrolyses AEA to AA and ETA Show undefined attributes

catalystActivity	[CatalystActivity:10522377] fatty acid amide hydrolase activity of FAAH [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10522379
displayName	FAAH hydrolyses AEA to AA and ETA
eventOf	[Pathway:R-SSC-2142753] Arachidonate metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5693742] FAAH hydrolyses AEA to AA and ETA - Homo sapiens
input	[SimpleEntity:R-ALL-5693754] AEA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FAAH hydrolyses AEA to AA and ETA H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine
output	[SimpleEntity:R-ALL-29768] AA [cytosol] [SimpleEntity:R-ALL-1498751] ETA [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5693742
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2142753] Arachidonate metabolism
(inferredTo)	[Reaction:R-HSA-5693742] FAAH hydrolyses AEA to AA and ETA

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