Reactome | ATXN3 binds VCP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10520702
displayName	ATXN3 binds VCP
eventOf	[Pathway:R-SSC-5689877] Josephin domain DUBs - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5688834] ATXN3 binds VCP - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-6783285] ATXN3 [nucleoplasm] [Complex:R-SSC-5643747] VCP hexamer [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ATXN3 binds VCP
output	[Complex:R-SSC-5688824] ATXN3:VCP hexamer [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5688834
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-5689877] Josephin domain DUBs
(inferredTo)	[Reaction:R-HSA-5688834] ATXN3 binds VCP

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