Reactome | TP53BP1 recruits DCLRE1C to ATM

Schema > Reaction > Entries

TP53BP1 recruits DCLRE1C to ATM Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10520352
displayName	TP53BP1 recruits DCLRE1C to ATM
eventOf	[Pathway:R-SSC-5693571] Nonhomologous End-Joining (NHEJ) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-5686704] Activated ATM phosphorylates DCLRE1C - Sus scrofa
inferredFrom	[Reaction:R-HSA-5686900] TP53BP1 recruits DCLRE1C to ATM - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-5686712] DCLRE1C [nucleoplasm] [Complex:R-SSC-5686692] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TP53BP1 recruits DCLRE1C to ATM
output	[Complex:R-SSC-5686907] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAX1IP:DCLRE1C [nucleoplasm]
precedingEvent	[Reaction:R-SSC-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5686900
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5693571] Nonhomologous End-Joining (NHEJ)
(precedingEvent)	[Reaction:R-SSC-5686704] Activated ATM phosphorylates DCLRE1C
(inferredTo)	[Reaction:R-HSA-5686900] TP53BP1 recruits DCLRE1C to ATM