Reactome | BRAP binds RAS:GTP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10518776
displayName	BRAP binds RAS:GTP
eventOf	[Pathway:R-SSC-5675221] Negative regulation of MAPK pathway - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-5674022] BRAP autoubiquitinates - Sus scrofa
inferredFrom	[Reaction:R-HSA-5674018] BRAP binds RAS:GTP - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-5672938] BRAP [cytosol] [Complex:R-SSC-109783] p21 RAS:GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	BRAP binds RAS:GTP
output	[Complex:R-SSC-5674003] p21 RAS:GTP:BRAP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5674018
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-5675221] Negative regulation of MAPK pathway
(precedingEvent)	[Reaction:R-SSC-5674022] BRAP autoubiquitinates
(inferredTo)	[Reaction:R-HSA-5674018] BRAP binds RAS:GTP

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