Reactome | NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10516687] DNA ligase activity of NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-SSC-5649734] LIG3 ligates NEIL1,NEIL2-generated single strand break - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10516676
displayName	NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-SSC-110340] Ghost homologue of SSB-dsDNA [nucleoplasm] [Complex:R-SSC-110338] LIG3:XRCC1 [nucleoplasm] [CandidateSet:R-SSC-5649697] NEIL1,NEIL2 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5649651] PNKP [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-53845] POLB [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5649733] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm] - Homo sapiens
maxDepth	3
name	NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA
producedByEvent	[Reaction:R-SSC-5649723] POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-5649733
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5649734] LIG3 ligates NEIL1,NEIL2-generated single strand break
(physicalEntity)	[CatalystActivity:10516687] DNA ligase activity of NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]
(output)	[Reaction:R-SSC-5649723] POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution
(inferredTo)	[Complex:R-HSA-5649733] NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]