Reactome | RHO GTPases Activate ROCKs

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557295
displayName	RHO GTPases Activate ROCKs
eventOf	[Pathway:R-SSC-195258] RHO GTPase Effectors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SSC-419049] ROCK activation by RHO - Sus scrofa [Reaction:R-SSC-9680443] ROCK1,2 bind ROCKi - Sus scrofa
inferredFrom	[Pathway:R-HSA-5627117] RHO GTPases Activate ROCKs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RHO GTPases Activate ROCKs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-5627117
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-195258] RHO GTPase Effectors
(hasEncapsulatedEvent)	[Pathway:R-SSC-2682334] EPH-Ephrin signaling [Pathway:R-SSC-376176] Signaling by ROBO receptors [Pathway:R-SSC-5625900] RHO GTPases activate CIT [Pathway:R-SSC-5627123] RHO GTPases activate PAKs
(inferredTo)	[Pathway:R-HSA-5627117] RHO GTPases Activate ROCKs

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