Reactome | EP400 binds CDKN1A promoter

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10510480
displayName	EP400 binds CDKN1A promoter
eventOf	[Pathway:R-SSC-2559586] DNA Damage/Telomere Stress Induced Senescence - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4647593] EP400 binds CDKN1A promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-3321987] EP400 [nucleoplasm] [Complex:R-SSC-3786257] p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	EP400 binds CDKN1A promoter
output	[Complex:R-SSC-4647605] EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-4647593
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-2559586] DNA Damage/Telomere Stress Induced Senescence
(inferredTo)	[Reaction:R-HSA-4647593] EP400 binds CDKN1A promoter

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