Reactome | SMURF2 binds AXIN

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10510326
displayName	SMURF2 binds AXIN
eventOf	[Pathway:R-SSC-4641257] Degradation of AXIN - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-4641129] AXIN is ubiquitinated by SMURF2 - Sus scrofa
inferredFrom	[Reaction:R-HSA-4641134] SMURF2 binds AXIN - Homo sapiens
input	[DefinedSet:R-SSC-3640819] AXIN [cytosol] [EntityWithAccessionedSequence:R-SSC-173537] SMURF2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SMURF2 binds AXIN
output	[Complex:R-SSC-4641136] AXIN:SMURF2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-4641134
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-4641257] Degradation of AXIN
(precedingEvent)	[Reaction:R-SSC-4641129] AXIN is ubiquitinated by SMURF2
(inferredTo)	[Reaction:R-HSA-4641134] SMURF2 binds AXIN

Cite Us!