Reactome | HuR binds mRNAs in the nucleus

Schema > Reaction > Entries

HuR binds mRNAs in the nucleus Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10480753
displayName	HuR binds mRNAs in the nucleus
eventOf	[Pathway:R-SSC-450520] HuR (ELAVL1) binds and stabilizes mRNA - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-450387] HuR binds the CRM1 nuclear export machinery - Sus scrofa
inferredFrom	[Reaction:R-HSA-450494] HuR binds mRNAs in the nucleus - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-450601] ELAVL1 [nucleoplasm] [OtherEntity:R-ALL-450613] mRNA Transcript Targeted by HuR with Unknown Phosphorylation [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	HuR binds mRNAs in the nucleus
output	[Complex:R-SSC-450395] HuR with Unknown Phosphorylation: mRNA Complex [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-450494
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-450520] HuR (ELAVL1) binds and stabilizes mRNA
(precedingEvent)	[Reaction:R-SSC-450387] HuR binds the CRM1 nuclear export machinery
(inferredTo)	[Reaction:R-HSA-450494] HuR binds mRNAs in the nucleus

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