Reactome | Acetylation of glucosamine 6-phosphate to GlcNAc6P

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Acetylation of glucosamine 6-phosphate to GlcNAc6P Show undefined attributes

catalystActivity	[CatalystActivity:10480351] glucosamine 6-phosphate N-acetyltransferase activity of 2xGNPNAT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10480353
displayName	Acetylation of glucosamine 6-phosphate to GlcNAc6P
eventOf	[Pathway:R-SSC-446210] Synthesis of UDP-N-acetyl-glucosamine - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-446185] Isomerization of GlcNAc6P to GlcNAc1P - Sus scrofa
inferredFrom	[Reaction:R-HSA-449734] Acetylation of glucosamine 6-phosphate to GlcNAc6P - Homo sapiens
input	[SimpleEntity:R-ALL-76183] Ac-CoA [cytosol] [SimpleEntity:R-ALL-449701] GlcN6P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Acetylation of glucosamine 6-phosphate to GlcNAc6P D-glucosamine 6-phosphate + acetyl-CoA => N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)
output	[SimpleEntity:R-ALL-449703] AcGlcN6P [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-SSC-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P - Sus scrofa [Reaction:R-SSC-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-449734
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-446210] Synthesis of UDP-N-acetyl-glucosamine
(precedingEvent)	[Reaction:R-SSC-446185] Isomerization of GlcNAc6P to GlcNAc1P
(inferredTo)	[Reaction:R-HSA-449734] Acetylation of glucosamine 6-phosphate to GlcNAc6P

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