Reactome | G-protein coupled bile acid receptor binds lithocholic acid

Schema > Reaction > Entries

G-protein coupled bile acid receptor binds lithocholic acid Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10479213
displayName	G-protein coupled bile acid receptor binds lithocholic acid
eventOf	[Pathway:R-SSC-373076] Class A/1 (Rhodopsin-like receptors) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-444654] G-protein coupled bile acid receptor binds lithocholic acid - Homo sapiens
input	[DefinedSet:R-ALL-444840] Bile acids [extracellular region] [EntityWithAccessionedSequence:R-SSC-444640] GPBAR1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	G-protein coupled bile acid receptor binds lithocholic acid
output	[Complex:R-SSC-444843] GPBAR1: Bile acids [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-444654
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-373076] Class A/1 (Rhodopsin-like receptors)
(inferredTo)	[Reaction:R-HSA-444654] G-protein coupled bile acid receptor binds lithocholic acid

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