Reactome | SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol

Schema > Reaction > Entries

SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10477989] choline transmembrane transporter activity of SLC5A7 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10477991
displayName	SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol
eventOf	[Pathway:R-SSC-264642] Acetylcholine Neurotransmitter Release Cycle - Sus scrofa [Pathway:R-SSC-9958517] SLC-mediated bile acid transport - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-264622] Cho is acetylated to AcCho by CHAT - Sus scrofa
inferredFrom	[Reaction:R-HSA-429594] SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-264638] Cho [extracellular region] [SimpleEntity:R-ALL-188972] Cl- [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol Sodium- and chloride-dependent choline transport by CHT
output	[SimpleEntity:R-ALL-264618] Cho [cytosol] [SimpleEntity:R-ALL-352022] Cl- [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-429594
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9958517] SLC-mediated bile acid transport [Pathway:R-SSC-264642] Acetylcholine Neurotransmitter Release Cycle
(precedingEvent)	[Reaction:R-SSC-264622] Cho is acetylated to AcCho by CHAT
(inferredTo)	[Reaction:R-HSA-429594] SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol

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