Reactome | SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+

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SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ Show undefined attributes

catalystActivity	[CatalystActivity:10477630] L-glutamate transmembrane transporter activity of SLC17A6,7,8 [synaptic vesicle membrane]
category	transition
compartment	[Compartment:201753] synaptic vesicle membrane [Compartment:70101] cytosol [Compartment:20600] synaptic vesicle
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10477632
displayName	SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+
eventOf	[Pathway:R-SSC-442660] SLC-mediated transport of neurotransmitters - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-428052] SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ - Homo sapiens
input	[SimpleEntity:R-ALL-428548] H+ [synaptic vesicle] [SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ Vesicular glutamate transport
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-428614] L-Glu [synaptic vesicle]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-428052
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-442660] SLC-mediated transport of neurotransmitters
(inferredTo)	[Reaction:R-HSA-428052] SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+

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