Reactome | HLCS biotinylates ACACB

Schema > Reaction > Entries

HLCS biotinylates ACACB Show undefined attributes

catalystActivity	[CatalystActivity:10505896] biotin--[biotin carboxyl-carrier protein] ligase activity of HLCS [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10509850
displayName	HLCS biotinylates ACACB
eventOf	[Pathway:R-SSC-196780] Biotin transport and metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4167511] HLCS biotinylates ACACB - Homo sapiens
input	[Complex:R-SSC-2993859] ACACB:2Mn2+ [mitochondrial outer membrane] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-199207] Btn [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	HLCS biotinylates ACACB
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-SSC-2993829] Btn-ACACB:2Mn2+ [mitochondrial outer membrane] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-SSC-199219] SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-4167511
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-196780] Biotin transport and metabolism
(inferredTo)	[Reaction:R-HSA-4167511] HLCS biotinylates ACACB