Reactome | Signal amplification

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557231
displayName	Signal amplification
eventOf	[Pathway:R-SSC-76002] Platelet activation, signaling and aggregation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SSC-392170] ADP signalling through P2Y purinoceptor 12 - Sus scrofa [Pathway:R-SSC-418592] ADP signalling through P2Y purinoceptor 1 - Sus scrofa [Pathway:R-SSC-428930] Thromboxane signalling through TP receptor - Sus scrofa
inferredFrom	[Pathway:R-HSA-392518] Signal amplification - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Signal amplification
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-392518
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-76002] Platelet activation, signaling and aggregation
(inferredTo)	[Pathway:R-HSA-392518] Signal amplification