Reactome | GPCR downstream signalling

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GPCR downstream signalling Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556085
displayName	GPCR downstream signalling
eventOf	[Pathway:R-SSC-372790] Signaling by GPCR - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:11091] G protein-coupled receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SSC-418555] G alpha (s) signalling events - Sus scrofa [Pathway:R-SSC-418594] G alpha (i) signalling events - Sus scrofa [Pathway:R-SSC-418597] G alpha (z) signalling events - Sus scrofa [Pathway:R-SSC-416476] G alpha (q) signalling events - Sus scrofa [Pathway:R-SSC-416482] G alpha (12/13) signalling events - Sus scrofa [Pathway:R-SSC-397795] G-protein beta:gamma signalling - Sus scrofa
inferredFrom	[Pathway:R-HSA-388396] GPCR downstream signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	11
name	GPCR downstream signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-388396
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-372790] Signaling by GPCR
(hasEncapsulatedEvent)	[Pathway:R-SSC-500792] GPCR ligand binding
(inferredTo)	[Pathway:R-HSA-388396] GPCR downstream signalling

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