Reactome | Plk1-mediated phosphorylation of Nlp

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Plk1-mediated phosphorylation of Nlp Show undefined attributes

catalystActivity	[CatalystActivity:10457004] protein serine/threonine kinase activity of p-T210-PLK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10473269
displayName	Plk1-mediated phosphorylation of Nlp
eventOf	[Pathway:R-SSC-380259] Loss of Nlp from mitotic centrosomes - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-380303] Dissociation of Phospho-Nlp from the centrosome - Sus scrofa
inferredFrom	[Reaction:R-HSA-380272] Plk1-mediated phosphorylation of Nlp - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-380268] centrosome [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Plk1-mediated phosphorylation of Nlp
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-380704] centrosome containing phosphorylated Nlp [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-380272
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-380259] Loss of Nlp from mitotic centrosomes
(precedingEvent)	[Reaction:R-SSC-380303] Dissociation of Phospho-Nlp from the centrosome
(inferredTo)	[Reaction:R-HSA-380272] Plk1-mediated phosphorylation of Nlp

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