Reactome | Kinetochore [cytosol]

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Kinetochore [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-375303] Microtubule-bound kinetochore [cytosol] - Sus scrofa [Complex:R-SSC-2484816] Sister Centromere:Kinetochore [chromosome, centromeric region] - Sus scrofa [Complex:R-SSC-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Sus scrofa [Complex:R-SSC-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-375302] Kinetochore capture of astral microtubules - Sus scrofa [Reaction:R-SSC-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Sus scrofa [Reaction:R-SSC-5666129] CDC42:GTP recruits DIAPH2-2 to kinetochores - Sus scrofa [Reaction:R-SSC-141409] Mad1 binds kinetochore - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10456931
displayName	Kinetochore [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-SSC-376244] AHCTF1 [cytosol] [EntityWithAccessionedSequence:R-SSC-377736] B9D2 [cytosol] [EntityWithAccessionedSequence:R-SSC-377888] BUB1 [cytosol] [Complex:R-SSC-377738] CCAN network [cytosol] [EntityWithAccessionedSequence:R-SSC-141412] CDC20 [cytosol] [EntityWithAccessionedSequence:R-SSC-375317] CENPA [cytosol] [EntityWithAccessionedSequence:R-SSC-376245] CENPE [cytosol] [EntityWithAccessionedSequence:R-SSC-376229] CENPF [cytosol] [Complex:R-SSC-377879] Chromosome passenger complex [cytosol] [EntityWithAccessionedSequence:R-SSC-377729] CKAP5 [cytosol] [EntityWithAccessionedSequence:R-SSC-376230] CLASP1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376252] CLASP2 [cytosol] [EntityWithAccessionedSequence:R-SSC-377732] CLIP1 [cytosol] [Complex:R-SSC-2029145] Dynein complex [cytosol] [EntityWithAccessionedSequence:R-SSC-376250] ERCC6L [cytosol] [DefinedSet:R-SSC-72361-3] Homologues of RPS27 [cytosol] [EntityWithAccessionedSequence:R-SSC-375311] INCENP [cytosol] [EntityWithAccessionedSequence:R-SSC-376239] KIF18A [cytosol] [EntityWithAccessionedSequence:R-SSC-376232] KIF2A [cytosol] [EntityWithAccessionedSequence:R-SSC-376259] KIF2B [cytosol] [EntityWithAccessionedSequence:R-SSC-376256] KIF2C [cytosol] [Complex:R-SSC-377745] KMN network [cytosol] [EntityWithAccessionedSequence:R-SSC-141433] MAD1L1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376240] MAPRE1 [cytosol] [Complex:R-SSC-377882] Mitotic checkpoint complex [cytosol] [EntityWithAccessionedSequence:R-SSC-376257] NDE1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376258] NDEL1 [cytosol] [EntityWithAccessionedSequence:R-SSC-377731] NUDC [cytosol] [Complex:R-SSC-377883] Nup107-160 complex [cytosol] [EntityWithAccessionedSequence:R-SSC-376249] PAFAH1B1 [cytosol] [EntityWithAccessionedSequence:R-SSC-164603] PLK1 [cytosol] [Complex:R-SSC-196206] PP2A [cytosol] [EntityWithAccessionedSequence:R-SSC-163443] PPP1CC [cytosol] [EntityWithAccessionedSequence:R-SSC-157703] RANBP2 [cytosol] [EntityWithAccessionedSequence:R-SSC-376255] RANGAP1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376235] RCC2 [cytosol] [Complex:R-SSC-377885] RZZ complex [cytosol] [EntityWithAccessionedSequence:R-SSC-376227] SGO1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376242] SGO2 [cytosol] [EntityWithAccessionedSequence:R-SSC-376228] SKA1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376231] SKA2 [cytosol] [EntityWithAccessionedSequence:R-SSC-377733] SPDL1 [cytosol] [EntityWithAccessionedSequence:R-SSC-376248] TAOK1 [cytosol] [EntityWithAccessionedSequence:R-SSC-165539] XPO1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-375305] Kinetochore [cytosol] - Homo sapiens
maxDepth	4
name	Kinetochore
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-375305
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-SSC-2484816] Sister Centromere:Kinetochore [chromosome, centromeric region] [Complex:R-SSC-2484902] Sister Centromere:Kinetochore:Microtubules [cytosol] [Complex:R-SSC-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] [Complex:R-SSC-375303] Microtubule-bound kinetochore [cytosol] [Complex:R-SSC-5666161] Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] [Complex:R-SSC-5666131] Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] [Complex:R-SSC-141441] Mad1:kinetochore complex [cytosol]
(input)	[Reaction:R-SSC-375302] Kinetochore capture of astral microtubules [Reaction:R-SSC-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 [Reaction:R-SSC-5666129] CDC42:GTP recruits DIAPH2-2 to kinetochores [Reaction:R-SSC-141409] Mad1 binds kinetochore
(inferredTo)	[Complex:R-HSA-375305] Kinetochore [cytosol]

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