Reactome | Nuclear Pore Complex (NPC) Disassembly

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10558039
displayName	Nuclear Pore Complex (NPC) Disassembly
eventOf	[Pathway:R-SSC-2980766] Nuclear Envelope Breakdown - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-2990882] CDK1 phosphorylates NUP98 - Sus scrofa [Reaction:R-SSC-2990880] NEK6/NEK7 phosphorylates NUP98 - Sus scrofa
inferredFrom	[Pathway:R-HSA-3301854] Nuclear Pore Complex (NPC) Disassembly - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Nuclear Pore Complex (NPC) Disassembly
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-3301854
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-2980766] Nuclear Envelope Breakdown
(inferredTo)	[Pathway:R-HSA-3301854] Nuclear Pore Complex (NPC) Disassembly

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