Reactome | HCAR1 binds LACT

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10507485
displayName	HCAR1 binds LACT
eventOf	[Pathway:R-SSC-3296197] Hydroxycarboxylic acid-binding receptors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3296326] HCAR1 binds LACT - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-3296280] HCAR1 [plasma membrane] [SimpleEntity:R-ALL-373863] LACT [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	HCAR1 binds LACT HCAR1 binds L-lactate
output	[Complex:R-SSC-3296263] HCAR1:LACT [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-3296326
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-3296197] Hydroxycarboxylic acid-binding receptors
(inferredTo)	[Reaction:R-HSA-3296326] HCAR1 binds LACT

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