Reactome | PHF20 binds TP53 dimethylated on K370 and K382

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10506801
displayName	PHF20 binds TP53 dimethylated on K370 and K382
eventOf	[Pathway:R-SSC-6804759] Regulation of TP53 Activity through Association with Co-factors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3222259] PHF20 binds TP53 dimethylated on K370 and K382 - Homo sapiens
input	[Complex:R-SSC-3222245] Me2-K370,K382-TP53 Tetramer [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-3222239] PHF20 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PHF20 binds TP53 dimethylated on K370 and K382
output	[Complex:R-SSC-3222249] PHF20:Me2-K370,K382-TP53 Tetramer [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-3222259
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-6804759] Regulation of TP53 Activity through Association with Co-factors
(inferredTo)	[Reaction:R-HSA-3222259] PHF20 binds TP53 dimethylated on K370 and K382

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