Reactome | Recruitment of GRB2:SOS to p-10Y-NTAL

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Recruitment of GRB2:SOS to p-10Y-NTAL Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10505213
displayName	Recruitment of GRB2:SOS to p-10Y-NTAL
eventOf	[Pathway:R-SSC-2730905] Role of LAT2/NTAL/LAB on calcium mobilization - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2730837] Recruitment of GRB2:SOS to p-10Y-NTAL - Homo sapiens
input	[Complex:R-SSC-2685672] p-SHC1:GRB2:SOS [cytosol] [EntityWithAccessionedSequence:R-SSC-2685597] phospho-p-10Y-LAT2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Recruitment of GRB2:SOS to p-10Y-NTAL
output	[Complex:R-SSC-2685692] p-10Y-NTAL:p-SHC1:GRB2:SOS [plasma membrane]
precedingEvent	[Reaction:R-SSC-2730844] Interaction of GRB2:SOS complex with p-SHC1 - Sus scrofa [Reaction:R-SSC-2730884] Phosphorylation of NTAL by p-SYK/Lyn - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2730837
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2730905] Role of LAT2/NTAL/LAB on calcium mobilization
(inferredTo)	[Reaction:R-HSA-2730837] Recruitment of GRB2:SOS to p-10Y-NTAL

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