Reactome | Prostaglandin E synthase isomerizes PGH2 to PGE2

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Prostaglandin E synthase isomerizes PGH2 to PGE2 Show undefined attributes

catalystActivity	[CatalystActivity:10469979] prostaglandin-E synthase activity of PTGES2(88-377), PTGES3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10469981
displayName	Prostaglandin E synthase isomerizes PGH2 to PGE2
eventOf	[Pathway:R-SSC-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-265295] Prostaglandin E synthase isomerizes PGH2 to PGE2 - Homo sapiens
input	[SimpleEntity:R-ALL-265283] PGH2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Prostaglandin E synthase isomerizes PGH2 to PGE2 prostaglandin H2 => prostaglandin E2
output	[SimpleEntity:R-ALL-265287] PGE2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-265295
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
(inferredTo)	[Reaction:R-HSA-265295] Prostaglandin E synthase isomerizes PGH2 to PGE2

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