Reactome | LRAT esterifies RBP1:atROL and FACYLs to atREs

Schema > Reaction > Entries

LRAT esterifies RBP1:atROL and FACYLs to atREs Show undefined attributes

catalystActivity	[CatalystActivity:10503692] O-palmitoyltransferase activity of LRAT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane [Compartment:876] plasma membrane [Compartment:13977] lipid droplet
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10503694
displayName	LRAT esterifies RBP1:atROL and FACYLs to atREs
eventOf	[Pathway:R-SSC-975634] Retinoid metabolism and transport - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2404137] LRAT esterifies RBP1:atROL and FACYLs to atREs - Homo sapiens
input	[SimpleEntity:R-ALL-429802] PC [plasma membrane] [Complex:R-SSC-74842] RBP1:atROL [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	LRAT esterifies RBP1:atROL and FACYLs to atREs all-trans-retinol--(retinol-binding protein) + a 1,2-diacyl-sn-glycero-3-phosphocholine => apo--(retinol-binding protein) + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine
output	[SimpleEntity:R-ALL-9982479] 2acPC [plasma membrane] [SimpleEntity:R-ALL-9982476] atRE [lipid droplet] [EntityWithAccessionedSequence:R-SSC-74841] RBP1 [cytosol]
precedingEvent	[Reaction:R-SSC-2404142] atROL binds RBP1 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2404137
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-975634] Retinoid metabolism and transport
(inferredTo)	[Reaction:R-HSA-2404137] LRAT esterifies RBP1:atROL and FACYLs to atREs

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