Reactome | HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+

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HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10501614
displayName	HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+
eventOf	[Pathway:R-SSC-2160916] Hyaluronan degradation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2160884] HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ - Homo sapiens
input	[Complex:R-SSC-2160889] HA:HAR:HYAL2 [plasma membrane] [Complex:R-SSC-5333682] SLC9A1:p-CHP:Ca2+ [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ HYAL2 interacts with NHE1 to create an acidic environment
output	[Complex:R-SSC-2160891] HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane]
precedingEvent	[Reaction:R-SSC-2160915] Receptor-mediated uptake of HA - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2160884
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2160916] Hyaluronan degradation
(inferredTo)	[Reaction:R-HSA-2160884] HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+

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