Reactome | Fibrillin 1,2,(3) [extracellular region]

Schema > CandidateSet > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-2396217] Fibrillins:BMP2,4,7,10,GF5 [extracellular region] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-2129385] MFAP2, MFAP5 bind microfibrils - Sus scrofa [Reaction:R-SSC-2396399] Fibrillins bind BMPs - Sus scrofa [Reaction:R-SSC-2485148] Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10493771
displayName	Fibrillin 1,2,(3) [extracellular region]
hasCandidate	[Polymer:R-SSC-2159866] Fibrillin-3 [extracellular region] - Sus scrofa
hasMember	[Polymer:R-SSC-2159861] Fibrillin-2 [extracellular region] - Sus scrofa
inDisease	false
inferredFrom	[CandidateSet:R-HSA-2159839] Fibrillin 1,2,(3) [extracellular region] - Homo sapiens
maxDepth	3
name	Fibrillin 1,2,(3)
producedByEvent	[Polymerisation:R-SSC-2129362] Fibrillin microfibril assembly - Sus scrofa
schemaClass	CandidateSet
species	[Species:49633] Sus scrofa
stId	R-SSC-2159839

(input)	[Reaction:R-SSC-2129385] MFAP2, MFAP5 bind microfibrils [Reaction:R-SSC-2396399] Fibrillins bind BMPs [Reaction:R-SSC-2485148] Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13
(hasComponent)	[Complex:R-SSC-2396217] Fibrillins:BMP2,4,7,10,GF5 [extracellular region] [Complex:R-SSC-2396329] Fibrilins:MFAP2,MFAP5 [extracellular region]
(output)	[Polymerisation:R-SSC-2129362] Fibrillin microfibril assembly
(inferredTo)	[CandidateSet:R-HSA-2159839] Fibrillin 1,2,(3) [extracellular region]

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