Reactome | CYP24A1 24-hydroxylates CTL

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CYP24A1 24-hydroxylates CTL Show undefined attributes

catalystActivity	[CatalystActivity:10468565] 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity of CYP24A1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10469217
displayName	CYP24A1 24-hydroxylates CTL
eventOf	[Pathway:R-SSC-211916] Vitamins - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-211950] CYP24A1 24-hydroxylates CTL - Homo sapiens
input	[SimpleEntity:R-ALL-215607] CTL [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix] [SimpleEntity:R-ALL-113533] O2 [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP24A1 24-hydroxylates CTL CYP24A1 catalyzes the initial step in the deactivation of the hormonally active form of vitamin D3
output	[SimpleEntity:R-ALL-215622] CTLA [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113563] NADP+ [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-211950
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-211916] Vitamins
(inferredTo)	[Reaction:R-HSA-211950] CYP24A1 24-hydroxylates CTL

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