Reactome | SFKs:p-KIT complex [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10491167] protein tyrosine kinase activity of SFKs:p-KIT complex [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-1433276] p-APS dimer:p-KIT complex [plasma membrane] - Sus scrofa [Complex:R-SSC-1433552] p-JAK2:SFKs:p-KIT complex [plasma membrane] - Sus scrofa [Complex:R-SSC-1470000] p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-205238] SHP2 interacts with p-KIT - Sus scrofa [Reaction:R-SSC-1472121] Phosphorylation of p-KIT on Y900 by Src kinases - Sus scrofa [Reaction:R-SSC-1433451] JAK2 binds to p-KIT - Sus scrofa [Reaction:R-SSC-205319] Interaction of APS and p-KIT - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10468425
displayName	SFKs:p-KIT complex [plasma membrane]
hasComponent	[Complex:R-SSC-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] [DefinedSet:R-SSC-211064] Src family tyrosine kinases (SFKs) [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-205271] SFKs:p-KIT complex [plasma membrane] - Homo sapiens
maxDepth	4
name	SFKs:p-KIT complex
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-205271
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-1472121] Phosphorylation of p-KIT on Y900 by Src kinases [Reaction:R-SSC-1433451] JAK2 binds to p-KIT [Reaction:R-SSC-205319] Interaction of APS and p-KIT [Reaction:R-SSC-205238] SHP2 interacts with p-KIT
(hasComponent)	[Complex:R-SSC-1470000] p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] [Complex:R-SSC-1469999] p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] [Complex:R-SSC-1433527] p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] [Complex:R-SSC-1433552] p-JAK2:SFKs:p-KIT complex [plasma membrane] [Complex:R-SSC-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] [Complex:R-SSC-205257] APS dimer:p-c-Kit:SFKs complex [plasma membrane] [Complex:R-SSC-1433276] p-APS dimer:p-KIT complex [plasma membrane] [Complex:R-SSC-205267] SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] [Complex:R-SSC-1433530] p-SHP2:p-KIT complex [plasma membrane]
(physicalEntity)	[CatalystActivity:10491167] protein tyrosine kinase activity of SFKs:p-KIT complex [plasma membrane]
(inferredTo)	[Complex:R-HSA-205271] SFKs:p-KIT complex [plasma membrane]

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