Reactome | Cell death signalling via NRAGE, NRIF and NADE

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556789
displayName	Cell death signalling via NRAGE, NRIF and NADE
eventOf	[Pathway:R-SSC-193704] p75 NTR receptor-mediated signalling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2133497] apoptotic signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-SSC-193648] NRAGE signals death through JNK - Sus scrofa [Pathway:R-SSC-205025] NADE modulates death signalling - Sus scrofa
inferredFrom	[Pathway:R-HSA-204998] Cell death signalling via NRAGE, NRIF and NADE - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Cell death signalling via NRAGE, NRIF and NADE
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-204998
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-193704] p75 NTR receptor-mediated signalling
(inferredTo)	[Pathway:R-HSA-204998] Cell death signalling via NRAGE, NRIF and NADE

Cite Us!