Reactome | NGF:p75NTR:NADE [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10468375] cysteine-type endopeptidase activator activity involved in apoptotic process of NGF:p75NTR:NADE [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-205018] NGF ligand:p75NTR:NADE:14-3-3epsilon [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-204981] 14-3-3epsilon attentuates NADE-related apoptosis - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10463981
displayName	NGF:p75NTR:NADE [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-SSC-194333] BEX3 [cytosol] [Complex:R-SSC-205123] mature NGF homodimer:p75NTR [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-204978] NGF:p75NTR:NADE [plasma membrane] - Homo sapiens
maxDepth	4
name	NGF:p75NTR:NADE
producedByEvent	[Reaction:R-SSC-193650] p75NTR binds to NADE - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-204978
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-204981] 14-3-3epsilon attentuates NADE-related apoptosis
(physicalEntity)	[CatalystActivity:10468375] cysteine-type endopeptidase activator activity involved in apoptotic process of NGF:p75NTR:NADE [plasma membrane]
(hasComponent)	[Complex:R-SSC-205018] NGF ligand:p75NTR:NADE:14-3-3epsilon [plasma membrane]
(output)	[Reaction:R-SSC-193650] p75NTR binds to NADE
(inferredTo)	[Complex:R-HSA-204978] NGF:p75NTR:NADE [plasma membrane]