Reactome | Sequestering and phosphorylation Fc gamma receptors in the lipid rafts

Schema > BlackBoxEvent > Entries

Sequestering and phosphorylation Fc gamma receptors in the lipid rafts Show undefined attributes

catalystActivity	[CatalystActivity:10499726] protein tyrosine kinase activity of Src family kinases (SFKs) [cytosol]
category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10499728
displayName	Sequestering and phosphorylation Fc gamma receptors in the lipid rafts
eventOf	[Pathway:R-SSC-2029481] FCGR activation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-2029452] Recruitment of SYK to phosphorylated ITAMs - Sus scrofa
inferredFrom	[BlackBoxEvent:R-HSA-2029459] Sequestering and phosphorylation Fc gamma receptors in the lipid rafts - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-2029146] clustered IgG-Ag:FCGRs [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Sequestering and phosphorylation Fc gamma receptors in the lipid rafts
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-2029128] clustered IgG-Ag:p-FCGRs [plasma membrane]
precedingEvent	[Reaction:R-SSC-2029455] Cross-linking of FCGRIA with IgG-coated Ag - Sus scrofa [Reaction:R-SSC-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-2029459
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2029481] FCGR activation
(precedingEvent)	[Reaction:R-SSC-2029452] Recruitment of SYK to phosphorylated ITAMs
(inferredTo)	[BlackBoxEvent:R-HSA-2029459] Sequestering and phosphorylation Fc gamma receptors in the lipid rafts

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