Reactome | clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10499696] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] - Sus scrofa [Complex:R-SSC-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR - Sus scrofa [Reaction:R-SSC-2029273] PI3K binds to p-6Y-SYK - Sus scrofa [Reaction:R-SSC-2029270] Recruitment of PLCgamma to membrane - Sus scrofa [Reaction:R-SSC-2029458] Recruitment of VAV1 to p-6Y-SYK - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10499662
displayName	clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
hasComponent	[Complex:R-SSC-2029128] clustered IgG-Ag:p-FCGRs [plasma membrane] [EntityWithAccessionedSequence:R-SSC-1861712] phospho-p-6Y-SYK [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - Homo sapiens
maxDepth	9
name	clustered IgG-Ag:p-FCGRs:p-6Y-SYK
producedByEvent	[Reaction:R-SSC-2029272] Release of PLCG from FCGR - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-2029158
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-2029458] Recruitment of VAV1 to p-6Y-SYK [Reaction:R-SSC-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR [Reaction:R-SSC-2029273] PI3K binds to p-6Y-SYK [Reaction:R-SSC-2029270] Recruitment of PLCgamma to membrane
(physicalEntity)	[CatalystActivity:10499696] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
(hasComponent)	[Complex:R-SSC-2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] [Complex:R-SSC-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] [Complex:R-SSC-2029131] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] [Complex:R-SSC-2029149] PI3K:p-6Y-SYK [plasma membrane] [Complex:R-SSC-2029137] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] [Complex:R-SSC-2029156] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane]
(output)	[Reaction:R-SSC-2029272] Release of PLCG from FCGR
(inferredTo)	[Complex:R-HSA-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]