Reactome | ICAM1-5 bind Integrin alphaLbeta2 (LFA-1)

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ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10465523
displayName	ICAM1-5 bind Integrin alphaLbeta2 (LFA-1)
eventOf	[Pathway:R-SSC-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell - Sus scrofa [Pathway:R-SSC-216083] Integrin cell surface interactions - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-199050] ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) - Homo sapiens
input	[DefinedSet:R-SSC-198193] ICAM 1-5 [plasma membrane] [Complex:R-SSC-198196] Integrin alphaLbeta2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ICAM1-5 bind Integrin alphaLbeta2 (LFA-1)
output	[Complex:R-SSC-198200] LFA-1:ICAM 1-5 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-199050
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell [Pathway:R-SSC-216083] Integrin cell surface interactions
(inferredTo)	[Reaction:R-HSA-199050] ICAM1-5 bind Integrin alphaLbeta2 (LFA-1)

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