Reactome | CYB5A:heme reduces Asc.- to AscH-

Schema > Reaction > Entries

CYB5A:heme reduces Asc.- to AscH- Show undefined attributes

catalystActivity	[CatalystActivity:10464891] alcohol dehydrogenase (NADP+) activity of CYB5A:heme [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10464893
displayName	CYB5A:heme reduces Asc.- to AscH-
eventOf	[Pathway:R-SSC-196836] Vitamin C (ascorbate) metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-198824] CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme - Sus scrofa
inferredFrom	[Reaction:R-HSA-198845] CYB5A:heme reduces Asc.- to AscH- - Homo sapiens
input	[SimpleEntity:R-ALL-1497805] Asc.- [cytosol] [Complex:R-SSC-198808] CYB5A:heme [mitochondrial outer membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CYB5A:heme reduces Asc.- to AscH- Reduction of semidehydroascorbate to ascorbate
output	[SimpleEntity:R-ALL-198816] AscH- [cytosol] [Complex:R-SSC-198772] CYB5A:ferriheme [mitochondrial outer membrane]
precedingEvent	[Reaction:R-SSC-198824] CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-198845
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-196836] Vitamin C (ascorbate) metabolism
(inferredTo)	[Reaction:R-HSA-198845] CYB5A:heme reduces Asc.- to AscH-
(precedingEvent)	[Reaction:R-SSC-198824] CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme

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