Reactome | Chondroitin polymerase complex transfers GlcA to CS chain

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Chondroitin polymerase complex transfers GlcA to CS chain Show undefined attributes

catalystActivity	[CatalystActivity:10496889] N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity of Chondroitin polymerase complex [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10496891
displayName	Chondroitin polymerase complex transfers GlcA to CS chain
eventOf	[Pathway:R-SSC-2022870] CS-GAG biosynthesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-1971487] Chondroitin polymerase complex transfers GalNAc to CS chain - Sus scrofa [Reaction:R-SSC-9632033] CSGALNACTs transfer GalNAc to CS chain - Sus scrofa
inferredFrom	[Reaction:R-HSA-1971491] Chondroitin polymerase complex transfers GlcA to CS chain - Homo sapiens
input	[DefinedSet:R-SSC-2064172] chondroitin(1)-core proteins [Golgi lumen] [SimpleEntity:R-ALL-1889970] UDP-GlcA [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Chondroitin polymerase complex transfers GlcA to CS chain A glucuronate moiety is added to chondroitin
output	[DefinedSet:R-SSC-2064050] chondroitin(2)-core proteins [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-SSC-1971482] CSGALNACTs transfer GalNAc to CS linker glycan - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-1971491
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2022870] CS-GAG biosynthesis
(precedingEvent)	[Reaction:R-SSC-9632033] CSGALNACTs transfer GalNAc to CS chain [Reaction:R-SSC-1971487] Chondroitin polymerase complex transfers GalNAc to CS chain
(inferredTo)	[Reaction:R-HSA-1971491] Chondroitin polymerase complex transfers GlcA to CS chain

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