Reactome | lactose + H2O => D-glucose + D-galactose

Schema > Reaction > Entries

lactose + H2O => D-glucose + D-galactose Show undefined attributes

catalystActivity	[CatalystActivity:10462858] lactase activity of LCT dimer [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10462860
displayName	lactose + H2O => D-glucose + D-galactose
eventOf	[Pathway:R-SSC-189085] Digestion of dietary carbohydrate - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol - Sus scrofa
inferredFrom	[Reaction:R-HSA-189062] lactose + H2O => D-glucose + D-galactose - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-188973] Lac [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	lactose + H2O => D-glucose + D-galactose Digestion of lactose to yield glucose and galactose
output	[SimpleEntity:R-ALL-188995] Gal [extracellular region] [SimpleEntity:R-ALL-70115] Glc [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-189062
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-SSC-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol
(hasEvent)	[Pathway:R-SSC-189085] Digestion of dietary carbohydrate
(inferredTo)	[Reaction:R-HSA-189062] lactose + H2O => D-glucose + D-galactose

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