Reactome | Synthesis of IP2, IP, and Ins in the cytosol

Schema > Pathway > Entries

Synthesis of IP2, IP, and Ins in the cytosol Show undefined attributes

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557865
displayName	Synthesis of IP2, IP, and Ins in the cytosol
eventOf	[Pathway:R-SSC-1483249] Inositol phosphate metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258976] inositol phosphate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-1855174] I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol - Sus scrofa [Reaction:R-SSC-1855222] I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane - Sus scrofa [Reaction:R-SSC-1855208] I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol - Sus scrofa [Reaction:R-SSC-1855211] I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol - Sus scrofa [Reaction:R-SSC-1855154] I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol - Sus scrofa [Reaction:R-SSC-1855180] I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol - Sus scrofa [Reaction:R-SSC-1855232] I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol - Sus scrofa [Reaction:R-SSC-1855202] I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol - Sus scrofa [Reaction:R-SSC-1855178] Glc6P is isomerised to I3P by ISYNA1 in the cytosol - Sus scrofa [Reaction:R-SSC-1855210] I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol - Sus scrofa [Reaction:R-SSC-5678327] MIOX oxidises Ins to GlcA - Sus scrofa
inferredFrom	[Pathway:R-HSA-1855183] Synthesis of IP2, IP, and Ins in the cytosol - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of IP2, IP, and Ins in the cytosol
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-1855183
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-1483249] Inositol phosphate metabolism
(inferredTo)	[Pathway:R-HSA-1855183] Synthesis of IP2, IP, and Ins in the cytosol

© 2026 Reactome

Cite Us!