Reactome | GRB2:GAB1:PIK3R1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-5654333] Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5654667] Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Sus scrofa [Reaction:R-SSC-5654659] Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 - Sus scrofa [Reaction:R-SSC-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Sus scrofa [Reaction:R-SSC-5654641] Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Sus scrofa [Reaction:R-SSC-5654594] Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Sus scrofa [Reaction:R-SSC-5654592] Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10462134
displayName	GRB2:GAB1:PIK3R1 [cytosol]
hasComponent	[Complex:R-SSC-179849] GRB2:GAB1 [cytosol] [EntityWithAccessionedSequence:R-SSC-74789] PIK3R1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-179864] GRB2:GAB1:PIK3R1 [cytosol] - Homo sapiens
maxDepth	3
name	GRB2:GAB1:PIK3R1
producedByEvent	[Reaction:R-SSC-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-179864
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5654667] Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-SSC-5654594] Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-SSC-5654659] Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 [Reaction:R-SSC-5654592] Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 [Reaction:R-SSC-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-SSC-5654641] Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
(hasComponent)	[Complex:R-SSC-5654333] Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654191] Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654185] Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654189] Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654186] Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654194] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654203] Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-SSC-5654199] Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane]
(output)	[Reaction:R-SSC-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1
(inferredTo)	[Complex:R-HSA-179864] GRB2:GAB1:PIK3R1 [cytosol]

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