Reactome | Cell surface:C3b:Bb:Properdin [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10461365] serine-type endopeptidase activity of Cell surface:C3b:Bb:Properdin [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-174554] C3b:Bb:C3b:Properdin [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-174551] Formation of alternative pathway C5 convertase - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10459216
displayName	Cell surface:C3b:Bb:Properdin [plasma membrane]
hasComponent	[Complex:R-SSC-166832] C3b [extracellular region] [OtherEntity:R-ALL-983438] Cell surface [plasma membrane] [EntityWithAccessionedSequence:R-SSC-173746] CFB(260-764) [plasma membrane] [Polymer:R-SSC-182548] Properdin oligomer [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-173752] Cell surface:C3b:Bb:Properdin [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-SSC-173750] C3 convertases [plasma membrane] - Sus scrofa
name	Cell surface:C3b:Bb:Properdin
producedByEvent	[Reaction:R-SSC-173754] Properdin stabilizes C3b:Bb bound to cell surfaces - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-173752
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-174551] Formation of alternative pathway C5 convertase
(physicalEntity)	[CatalystActivity:10461365] serine-type endopeptidase activity of Cell surface:C3b:Bb:Properdin [plasma membrane]
(output)	[Reaction:R-SSC-173754] Properdin stabilizes C3b:Bb bound to cell surfaces
(hasComponent)	[Complex:R-SSC-174554] C3b:Bb:C3b:Properdin [plasma membrane]
(hasMember)	[DefinedSet:R-SSC-173750] C3 convertases [plasma membrane]
(inferredTo)	[Complex:R-HSA-173752] Cell surface:C3b:Bb:Properdin [plasma membrane]

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