Reactome | ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10489020] ligand-gated calcium channel activity of ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
componentOf	[Complex:R-SSC-5226920] AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5226904] AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10489019
displayName	ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]
hasComponent	[DefinedSet:R-SSC-111877] Ca-channel (closed) [endoplasmic reticulum membrane] 4 × [SimpleEntity:R-ALL-114520] I(1,4,5)P3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-169696] ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] - Homo sapiens
maxDepth	4
name	ITPR:I(1,4,5)P3 tetramer
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-169696
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5226904] AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it
(physicalEntity)	[CatalystActivity:10489020] ligand-gated calcium channel activity of ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]
(hasComponent)	[Complex:R-SSC-5226920] AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]
(inferredTo)	[Complex:R-HSA-169696] ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane]

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