Reactome | MMP14:TIMP2:MMP2 intermediate form [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10493988] serine-type endopeptidase activity of MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-SSC-1604368] Autocatalytic activation of bound proMMP2 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10493973
displayName	MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
hasComponent	[Complex:R-SSC-1604365] MMP14:TIMP2 [plasma membrane] [EntityWithAccessionedSequence:R-SSC-1604345] MMP2(67-660) [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-1604373] MMP14:TIMP2:MMP2 intermediate form [plasma membrane] - Homo sapiens
maxDepth	3
name	MMP14:TIMP2:MMP2 intermediate form
producedByEvent	[Reaction:R-SSC-1604360] Initial activation of proMMP2 by MMP14 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-1604373
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-1604368] Autocatalytic activation of bound proMMP2
(physicalEntity)	[CatalystActivity:10493988] serine-type endopeptidase activity of MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(output)	[Reaction:R-SSC-1604360] Initial activation of proMMP2 by MMP14
(inferredTo)	[Complex:R-HSA-1604373] MMP14:TIMP2:MMP2 intermediate form [plasma membrane]

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