Reactome | COX reactions

Schema > Pathway > Entries

compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556229
displayName	COX reactions
eventOf	[Pathway:R-SSC-211945] Phase I - Functionalization of compounds - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9971] prostanoid metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-140355] Arachidonate is oxidised to PGG2 by PTGS1 - Sus scrofa [Reaction:R-SSC-140359] PGG2 is reduced to PGH2 by PTGS1 - Sus scrofa
inferredFrom	[Pathway:R-HSA-140180] COX reactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	COX reactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-140180
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-211945] Phase I - Functionalization of compounds
(inferredTo)	[Pathway:R-HSA-140180] COX reactions