Reactome | TWIK related potassium channel (TREK)

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557729
displayName	TWIK related potassium channel (TREK)
eventOf	[Pathway:R-SSC-1296346] Tandem pore domain potassium channels - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1042694] potassium ion transmembrane transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-1296348] Activation of TWIK-related K+ channel (TREK) - Sus scrofa
inferredFrom	[Pathway:R-HSA-1299503] TWIK related potassium channel (TREK) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	TWIK related potassium channel (TREK)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-1299503
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-1296346] Tandem pore domain potassium channels
(inferredTo)	[Pathway:R-HSA-1299503] TWIK related potassium channel (TREK)

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