Reactome | Lyn activates ERK

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Lyn activates ERK Show undefined attributes

catalystActivity	[CatalystActivity:10489033] non-membrane spanning protein tyrosine kinase activity of Growth Hormone:Growth Hormone Receptor-JAK2 dimer:LYN [plasma membrane]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10489035
displayName	Lyn activates ERK
eventOf	[Pathway:R-SSC-982772] Growth hormone receptor signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1168459] Lyn activates ERK - Homo sapiens
input	4 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-SSC-169291] MAPKs [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Lyn activates ERK
output	4 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-SSC-169289] p-T,Y MAPKs [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-1168459
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-982772] Growth hormone receptor signaling
(inferredTo)	[BlackBoxEvent:R-HSA-1168459] Lyn activates ERK