Reactome | Formation of DSIF:NELF:early elongation complex

Schema > Reaction > Entries

Formation of DSIF:NELF:early elongation complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10455200
displayName	Formation of DSIF:NELF:early elongation complex
eventOf	[Pathway:R-SSC-113418] Formation of the Early Elongation Complex - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-113409] Abortive termination of early transcription elongation by DSIF:NELF - Sus scrofa [Reaction:R-SSC-112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - Sus scrofa
inferredFrom	[Reaction:R-HSA-113402] Formation of DSIF:NELF:early elongation complex - Homo sapiens
input	[Complex:R-SSC-112432] NELF complex [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-SSC-113406] RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of DSIF:NELF:early elongation complex
output	[Complex:R-SSC-113408] DSIF:NELF:early elongation complex [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
precedingEvent	[Reaction:R-SSC-113407] DSIF complex binds to RNA Pol II (hypophosphorylated) - Sus scrofa [Reaction:R-SSC-112437] Formation of NELF complex - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-113402
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-113418] Formation of the Early Elongation Complex
(precedingEvent)	[Reaction:R-SSC-113409] Abortive termination of early transcription elongation by DSIF:NELF [Reaction:R-SSC-112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex
(inferredTo)	[Reaction:R-HSA-113402] Formation of DSIF:NELF:early elongation complex