Reactome | Calmodulin activates Cam-PDE 1

Schema > Reaction > Entries

category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10454803
displayName	Calmodulin activates Cam-PDE 1
eventOf	[Pathway:R-SSC-111957] Cam-PDE 1 activation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-111955] cAMP hydrolysis by Cam-PDE 1 - Sus scrofa
inferredFrom	[Reaction:R-HSA-111956] Calmodulin activates Cam-PDE 1 - Homo sapiens
input	[DefinedSet:R-SSC-111952] PDE1 dimers [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Calmodulin activates Cam-PDE 1
output	[DefinedSet:R-SSC-9014905] activated PDE1 dimers [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-111956
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-111957] Cam-PDE 1 activation
(precedingEvent)	[Reaction:R-SSC-111955] cAMP hydrolysis by Cam-PDE 1
(inferredTo)	[Reaction:R-HSA-111956] Calmodulin activates Cam-PDE 1

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