Reactome | RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SSC-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] - Sus scrofa [Complex:R-SSC-113722] Aborted elongation complex after arrest [nucleoplasm] - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10449819
displayName	RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-SSC-113420] phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63504] POLR2B [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63506] POLR2C [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63508] POLR2D [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-83713] POLR2E [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-83714] POLR2F [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63517] POLR2G [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63523] POLR2H [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63525] POLR2I [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63531] POLR2J [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-63537] POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-83715] POLR2L [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] - Homo sapiens
maxDepth	2
name	RNA Polymerase II holoenzyme complex (hyperphosphorylated)
producedByEvent	[Reaction:R-SSC-113429] Elongating transcript encounters a lesion in the template - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-109909
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-SSC-113429] Elongating transcript encounters a lesion in the template
(hasComponent)	[Complex:R-SSC-113722] Aborted elongation complex after arrest [nucleoplasm] [Complex:R-SSC-6781822] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-SSC-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] [Complex:R-SSC-113425] RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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