Reactome | OMA1 hydrolyzes YME1L1

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OMA1 hydrolyzes YME1L1 Show undefined attributes

catalystActivity	[CatalystActivity:11077230] metalloendopeptidase activity of OMA1(144-447):Zn2+ [mitochondrial inner membrane]
category	omitted
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11077232
displayName	OMA1 hydrolyzes YME1L1
eventOf	[Pathway:R-SPO-9840373] Cellular response to mitochondrial stress - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9840564] OMA1 hydrolyzes YME1L1 - Homo sapiens
input	[Complex:R-SPO-9839129] YME1L1:Zn2+ hexamer [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	OMA1 hydrolyzes YME1L1
output	6 × [SimpleEntity:R-ALL-3777117] Zn2+ [mitochondrial intermembrane space]
regulatedBy	[NegativeRegulation:9840566] Negative regulation by 'ATP [mitochondrial intermembrane space]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9840564
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9840373] Cellular response to mitochondrial stress
(inferredTo)	[BlackBoxEvent:R-HSA-9840564] OMA1 hydrolyzes YME1L1