Reactome | AFG3L2 binds mitochondrial inner membrane proteins

Schema > Reaction > Entries

AFG3L2 binds mitochondrial inner membrane proteins Show undefined attributes

category	binding
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11077198
displayName	AFG3L2 binds mitochondrial inner membrane proteins
eventOf	[Pathway:R-SPO-9837999] Mitochondrial protein degradation - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SPO-9839113] AFG3L2 degrades mitochondrial inner membrane proteins - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-9838627] AFG3L2 binds mitochondrial inner membrane proteins - Homo sapiens
input	[Complex:R-SPO-9838620] AFG3L2:Zn2+ hexamer [mitochondrial inner membrane] [DefinedSet:R-SPO-9839144] Substrate of AFG3L2 (mitochondrial inner membrane) [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	AFG3L2 binds mitochondrial inner membrane proteins
output	[Complex:R-SPO-9838615] AFG3L2:substrate protein (mitochondrial inner membrane) [mitochondrial inner membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9838627
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9837999] Mitochondrial protein degradation
(precedingEvent)	[BlackBoxEvent:R-SPO-9839113] AFG3L2 degrades mitochondrial inner membrane proteins
(inferredTo)	[Reaction:R-HSA-9838627] AFG3L2 binds mitochondrial inner membrane proteins

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