Reactome | CHMP7 binds LEMD2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11075804
displayName	CHMP7 binds LEMD2
eventOf	[Pathway:R-SPO-9668328] Sealing of the nuclear envelope (NE) by ESCRT-III - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9668335] CHMP7 binds LEMD2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-3067329] lem2 [nuclear envelope] [EntityWithAccessionedSequence:R-SPO-917703] snf7 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CHMP7 binds LEMD2
output	[Complex:R-SPO-9668512] LEMD2:CHMP7 [nuclear envelope]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9668335
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-9668328] Sealing of the nuclear envelope (NE) by ESCRT-III
(inferredTo)	[Reaction:R-HSA-9668335] CHMP7 binds LEMD2